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An NIH institute (NIDDK) advises that health care providers should consider testing people who have severe and continuing fatigue, unexplained cirrhosis, joint pain or arthritis, heart problems, erectile dysfunction, or diabetes, because these health issues may result from hemochromatosis. The team found that men and women with the mutations, aged 65 to 70, were much more likely to suffer from frailty and chronic pain and had lower muscle strength. They can categorically mention about the onset of pain just few months before or after diabetes showed its presence. For example, they may interact with other prescription drugs containing nitrates, which are often taken by people with diabetes or heart disease, and lower blood pressure to dangerous levels, the agency wrote. According to several large surveys, up to 33.7 percent of people experience some form of anxiety disorder during their lifetime. 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